JUVENILE DELINQUENCY AMONG MINORITIES COMPARED TO NON-HISPANIC WHITES Research Paper

JUVENILE DELINQUENCY AMONG MINORITIES COMPARED TO NON-HISPANIC WHITES - Research Paper Example ermining the nature of a child but in order to solve the problem related to childhood delinquency the most important aspect is to realize the requirement of a child and provide him with proper emotional nourishment, going beyond the extent of social, cultural or religious discrimination. At the same time, parents also have to be more tolerant and understanding; consequently they must also realize that their arbitrary actions can harm the child worst in their psychology. Providing proper support to children, especially when it comes from parents, is the best possible way to reduce the problems related to juvenile delinquency. The increasing peace of social cosmopolitanism, though on several occasions, has been encouraged by sociologists with the expectation that it reflects the ideals of social tolerance and harmonized existence, however, in reality, the entire situation is far from being real. Globalization, evolution of human rights and revoking the principles of universal brotherhood are some of the important factors that aspired scholars, intellectual and common people to wish for a better socio-cultural existence. The reality has emerged as quite contradictory to the expected situation and by remaining far from realizing the basic aspects of human existence, people have remained hostile against accepting religious, racial and cultural differences normally and they have remained on an uncompromising stance in providing adequate recognition to their fellow counterparts that have different social, religious and cultural upbringing. The social structure of nations like the United States is a bright exam ple in support of the observation as cultural and racial conflicts are predominating factors, emerging as essential barriers when it comes to attainment of social tranquility and harmony. Among several factors, such as, racial tensions, cultural discrimination and socio-religious oppression, juvenile delinquency among minorities is one of the most predominating

Lactate & Enzymes Essay Example | Topics and Well Written Essays - 1750 words

Lactate & Enzymes - Essay Example If pyruvate does not break down, it usually turns into lactate. When pyruvate is produced, the muscle cell will try to use it for aerobic energy. However, if the cell does not have the capacity to use all the pyruvate produced, it will be changed chemically to lactate. Some cells have a large capacity to use pyruvate for aerobic energy while others have very little. With training, many cells can adapt to use more pyruvate and, thus, produce less lactate. Lactate is present in our system at rest and as we go about our every day activities, although at low levels. However, as exercise or work activity increases in intensity, large amounts of pyruvate are produced very quickly. Because pyruvate can be produced quickly, not all of it may be used for aerobic energy. The surplus pyruvate will turn into lactate. This is why lactate is such a significant marker for training. When it is produced, it is a sign that aerobic energy is limited during the activity. There is a different reason why more lactate is produced as exercise intensity increases. As exercise increases, extra muscle fibers will be recruited. These fibers are used infrequently at rest or in light activity. Fast twitch fibers are not very good at turning pyruvate into aerobic energy. Hence, a lot of this pyruvate turns into lactate. Lactate is a major metabolic intermediate. Its fate depends on the conditions of the cell. In aerobic oxidation of glucose, glucose is converted to pyruvate, which is then converted to acetylSCoA (or AcetylCoA), a high-energy thioester. Under anaerobic conditions, pyruvate is reduced to lactate to regenerate the NAD + needed in Step 6 of glycolysis to keep glycolysis pathway going. 3. Which enzyme is responsible for lactate production Write out the equation for this reaction. Lactate Dehydrogenase (LDH) is an enzyme responsible for lactate production, which is present in varieties or organisms including plants and animals. This will catalyse the inter-conversion of pyruvate and lactate with concomitant inter-conversion of NADH and NAD+. As it can also catalyze the oxidation of hydroxybutyrate, occasionally called Hydroxybutyrate Dehydrogenase (HBD). Or D(-)Lactate + -NAD + Hydrazine LDH> Pyruvate Hydrazone + -NADH Abbreviations used: -NAD = -Nicotinamide Adenine Dinucleotide, Oxidized Form -NADH = -Nicotinamide Adenine Dinucleotide, Reduced Form LDH = D-Lactic Dehydrogenase 4. The student decided to use this enzyme to measure blood lactate levels. He reasoned that if he could produce reaction conditions that allowed the enzyme to metabolise all the lactate present, he would be able to calculate the lactate content of his sample by reading the change in absorbance at 340nm. Explain the reasoning behind this idea. LDH catalyzes the reduction of pyruvate to L-lactate with concomitant oxidation of NADH2 to NAD. Since the oxidation of NADH2 is directly proportional to the reduction of pyruvate in equimolar amounts, the LDH activity can be calculated from the rate of decrease in absorbance at 340 nm (334 nm or 365 nm). 5. In order to obtain suitable conditions for an assay to measure plasma lactate levels, the student chose a buffer containing 1.5% (w/v) hydrazine. Hydrazine reacts covalently with pyruvate to form a hydrazone: CH3 CH3 | | C=O + NH2.NH2 C=N.NH2+H20 |